MicroRNA-370 suppresses the retinal capillary endothelial cell growth by targeting KDR gene
نویسندگان
چکیده
منابع مشابه
Hypoxia regulates vascular endothelial growth factor receptor KDR/Flk gene expression through adenosine A2 receptors in retinal capillary endothelial cells.
PURPOSE Vascular endothelial growth factor (VEGF) is an endothelial cell-specific angiogenic factor that serves an important role in numerous ischemic retinopathies. The authors studied the hypoxic gene regulation of two known VEGF receptors (KDR and Flt) and its mechanism in cultured bovine retinal endothelial cells (BREC). METHODS Confluent monolayers of BREC were exposed to various oxygen ...
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ژورنال
عنوان ژورنال: Bratislava Medical Journal
سال: 2017
ISSN: 1336-0345
DOI: 10.4149/bll_2017_040